Anticorps Polyclonal de lapin anti-FANCA-Specific

FANCA-Specific Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 19542-1-AP

Synonymes

FA, FA H, FA1, FAA, FACA, FAH, FANCA, FANCA-Specific, FANCH, Fanconi anemia group A protein, Protein FACA

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Galerie de données de validation

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  WB analysis of HeLa using 19542-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 19542-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 19542-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules HEK-293

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

19542-1-AP cible FANCA-Specific dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: Fanconi anemia, complementation group A
• Masse moléculaire calculée: 163 kDa
• Poids moléculaire observé: 163 kDa
• Numéro d’acquisition GenBank: NM_000135
• Symbole du gène: FANCA
• Identification du gène (NCBI): 2175
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.

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