Anticorps Polyclonal de lapin anti-FBP1

• Phare
• Validé par KD/KO

FBP1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12842-1-PBS

Synonymes

Liver FBPase, Fructose-1,6-bisphosphatase 1, FBPase 1, FBP, EC:3.1.3.11

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Galerie de données de validation

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  WB analysis of MCF-7 using 12842-1-AP (same clone as 12842-1-PBS)

  WB result of FBP1 antibody (12842-1-AP; 1:40000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FBP1 transfected MCF-7 cells. This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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  WB analysis using 12842-1-AP (same clone as 12842-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12842-1-AP (FBP1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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  WB analysis of human liver using 12842-1-AP (same clone as 12842-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 12842-1-AP (FBP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 12842-1-AP (same clone as 12842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 12842-1-AP (FBP1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 12842-1-AP (same clone as 12842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 12842-1-AP (FBP1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 12842-1-AP (same clone as 12842-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using FBP1 antibody (12842-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 12842-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12842-1-PBS cible FBP1 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FBP1 Protéine recombinante Ag3837
• Nom complet: fructose-1,6-bisphosphatase 1
• Masse moléculaire calculée: 338 aa, 37 kDa
• Poids moléculaire observé: 37-40 kDa
• Numéro d’acquisition GenBank: BC012927
• Symbole du gène: FBP1
• Identification du gène (NCBI): 2203
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FBP1 (Fructose-1,6-bisphosphatase 1) is also named as FBP and belongs to the FBPase class 1 family. It catalyzes the hydrolysis of fructose-1,6 bisphosphate to fructose-6-phosphate and inorganic phosphate. This reaction is an important regulatory site of gluconeogenesis. Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) (PMID:12126934).

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