Anticorps Polyclonal de lapin anti-fibrosin

fibrosin Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

ELISA

Conjugaison

Non conjugué

N° de cat : 11356-1-AP

Synonymes

FBRS, Probable fibrosin-1, FBSH, FBS1, FBS

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Galerie de données de validation

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  WB analysis of mouse kidney using 11356-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of MCF-7 using 11356-1-AP

  MCF7 cells were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Informations sur le produit

11356-1-AP cible fibrosin dans les applications de ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: fibrosin Protéine recombinante Ag1870
• Nom complet: fibrosin
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 48-52 kDa
• Numéro d’acquisition GenBank: BC014212
• Symbole du gène: fibrosin
• Identification du gène (NCBI): 64319
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation FBRS (or FBS1) gene, encoding fibrosin (or fibrosin-1), was first cloned by Prakash et al. and was found to be able to stimulate several biological activities related to scarring as a fibrogenic lymphokine. Fibrosin is secreted by activated lymphocytes that induce fibroblast proliferation. In vitro application of fibrosin stimulates expression of alpha smooth muscle actin fibers and plays an important role in up regulating the appearance of myofibroblasts during wound healing and possibly in fibrotic diseases. Fibrosin is also implicated in alcohol-induced hepatic fibrosis in vivo.

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