Anticorps Recombinant de lapin anti-FBXL13

FBXL13 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251880F12

N° de cat : 86857-1-PBS

Synonymes

DRC6, Dynein regulatory complex subunit 6, FBL13, F-box and leucine-rich repeat protein 13, F-box/LRR-repeat protein 13

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Galerie de données de validation

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  WB analysis using 86857-1-RR (same clone as 86857-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86857-1-RR (FBXL13 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86857-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86857-1-PBS cible FBXL13 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FBXL13 Protéine recombinante Ag10903
• Nom complet: F-box and leucine-rich repeat protein 13
• Masse moléculaire calculée: 707 aa, 81 kDa
• Poids moléculaire observé: 84 kDa
• Numéro d’acquisition GenBank: BC031285
• Symbole du gène: FBXL13
• Identification du gène (NCBI): 222235
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FBXL13, also known as F-box and leucine-rich repeat protein 13, is a human protein-coding gene located on chromosome 7q22.1. It is a member of the F-box protein family, characterized by an approximately 40-amino acid F-box motif. FBXL13 is part of the SCF-type E3 ubiquitin ligase complex, which plays a role in protein ubiquitination and degradation. The gene has multiple isoforms, including 84 kDa, 81 kDa, 79 kDa, and 53 kDa variants. While its specific function within the complex is not fully understood, FBXL13 has been implicated in regulating centrosome homeostasis and cell migration by directing the proteolysis of CEP192. Additionally, it may play a role in circadian rhythms by ubiquitinating and mediating the degradation of cryptochrome proteins.

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