Anticorps Polyclonal de lapin anti-FBXO16

FBXO16 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32063-1-PBS

Synonymes

F box only protein 16, F box protein 16, FBX16

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Galerie de données de validation

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  WB analysis using 32063-1-AP (same clone as 32063-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32063-1-AP (FBXO16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32063-1-PBS in a different storage buffer formulation.

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  IP experiment of T-47D using 32063-1-AP (same clone as 32063-1-PBS)

  IP result of anti-FBXO16 (IP:32063-1-AP, 4ug; Detection:32063-1-AP 1:1000) with T-47D cells lysate 1120 ug. This data was developed using the same antibody clone with 32063-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32063-1-PBS cible FBXO16 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FBXO16 Protéine recombinante Ag36230
• Nom complet: F-box protein 16
• Masse moléculaire calculée: 292 aa, 35 kDa
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC074986
• Symbole du gène: FBXO16
• Identification du gène (NCBI): 157574
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FBXO16 is a member of the F-box protein family, which functions as a substrate recognition subunit of the SCF (Skp1-Cullin-F-box) E3 ubiquitin ligase complex. High expression levels of FBXO16 are associated with better prognosis in cancer patients. For example, in ovarian cancer, patients with higher FBXO16 expression tend to have a more favorable outcome (PMID: 34333526). This suggests that FBXO16 could serve as a potential biomarker for cancer prognosis and therapeutic targeting.

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