Anticorps Recombinant de lapin anti-FCER1G

FCER1G Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242829E3

N° de cat : 85390-2-PBS

Synonymes

242829E3, Fc epsilon RI gamma, Fc receptor gamma-chain, Fc-epsilon RI-gamma, FceRI gamma

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Galerie de données de validation

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  WB analysis using 85390-2-RR (same clone as 85390-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85390-2-RR (FCER1G antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85390-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85390-2-RR

  Biolayer interferometry (BLl) kinetic assays of 85390-2-RR against Human FCER1G were performed. The affinity constant is 1.16 nM.

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Informations sur le produit

85390-2-PBS cible FCER1G dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, souris

• Réactivité: Humain, porc, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FCER1G Protéine recombinante Ag4442
• Nom complet: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
• Masse moléculaire calculée: 87 aa, 10 kDa
• Poids moléculaire observé: 10 kDa
• Numéro d’acquisition GenBank: BC033872
• Symbole du gène: FcRγ
• Identification du gène (NCBI): 2207
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FCER1G (Fc receptor gamma-chain, FcRgamma), also known as Fc-epsilon RI-gamma, or IgE Fc receptor subunit gamma (FceRI gamma), is a component of the high-affinity immunoglobulin E (IgE) receptor (Fc epsilon RI) which is a tetrameric complex of one alpha subunit, one beta subunit, and two disulfide-linked gamma subunits (PMID: 2146219; 2531187). Fc epsilon RI is present exclusively on mast cells and basophils, mediating allergic inflammatory signaling (PMID: 17438574). FCER1G is widely expressed and contains an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors (PMID: 19098920).

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