Anticorps Recombinant de lapin anti-FCRL1

FCRL1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

251080E1

N° de cat : 98557-1-PBS

Synonymes

CD307a, Fc receptor-like protein 1, FcRH1, FcR-like protein 1, IFGP family protein 1

---

Galerie de données de validation

• 

  FC experiment of human PBMCs using 98557-1-RR (same clone as 98557-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98557-1-RR (same clone as 98557-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected CHO using 98557-1-RR (same clone as 98557-1-PBS)

  1x10^6 CHO Cells (left) or FCRL1(CD307a)-transfected CHO Cells (right) were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

98557-1-PBS cible FCRL1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FCRL1 Protéine recombinante Eg3713
• Nom complet: Fc receptor-like 1
• Masse moléculaire calculée: 429 aa, 47 kDa
• Numéro d’acquisition GenBank: BC033690
• Symbole du gène: FCRL1
• Identification du gène (NCBI): 115350
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Fc receptor-like protein 1 (FCRL1) is a type I transmembrane glycoprotein that plays a crucial role in regulating B-cell receptor (BCR)-mediated signaling responses (PMID:15479727). It contains intracellular tyrosine-based motifs that can modulate BCR signaling, leading to changes in calcium flux, proliferation, and antibody production (PMID: 37822931). FCRL1 is involved in regulating B-cell development and activation, with its signaling pathways influencing ERK activation through interactions with proteins such as GRB2. This regulation is essential for maintaining B-cell homeostasis and preventing the development of autoreactive B cells (PMID: 34697226).

{{ptg:RelatedPrimaryAntibodies}}