Anticorps Recombinant de lapin anti-FCRL1

FCRL1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

251080E1

N° de cat : 98557-1-RR

Synonymes

CD307a, Fc receptor-like protein 1, FcRH1, FcR-like protein 1, IFGP family protein 1

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Galerie de données de validation

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  FC experiment of human PBMCs using 98557-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of human PBMCs using 98557-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Transfected CHO using 98557-1-RR

  1x10^6 CHO Cells (left) or FCRL1(CD307a)-transfected CHO Cells (right) were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines, Transfected CHO cells

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98557-1-RR cible FCRL1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FCRL1 Protéine recombinante Eg3713
• Nom complet: Fc receptor-like 1
• Masse moléculaire calculée: 429 aa, 47 kDa
• Numéro d’acquisition GenBank: BC033690
• Symbole du gène: FCRL1
• Identification du gène (NCBI): 115350
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Fc receptor-like protein 1 (FCRL1) is a type I transmembrane glycoprotein that plays a crucial role in regulating B-cell receptor (BCR)-mediated signaling responses (PMID:15479727). It contains intracellular tyrosine-based motifs that can modulate BCR signaling, leading to changes in calcium flux, proliferation, and antibody production (PMID: 37822931). FCRL1 is involved in regulating B-cell development and activation, with its signaling pathways influencing ERK activation through interactions with proteins such as GRB2. This regulation is essential for maintaining B-cell homeostasis and preventing the development of autoreactive B cells (PMID: 34697226).

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