Anticorps Polyclonal de lapin anti-FDX1L

FDX1L Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32790-1-PBS

Synonymes

Adrenodoxin-like protein, FDX2, Ferredoxin-1-like protein, Ferredoxin-2, mitochondrial

---

Galerie de données de validation

• 

  WB analysis using 32790-1-AP (same clone as 32790-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32790-1-AP (FDX1L antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32790-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

32790-1-PBS cible FDX1L dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FDX1L Protéine recombinante Ag37104
• Nom complet: ferredoxin 1-like
• Masse moléculaire calculée: 183 aa, 20 kDa
• Poids moléculaire observé: 21 kDa
• Numéro d’acquisition GenBank: BC063460
• Symbole du gène: FDX1L
• Identification du gène (NCBI): 112812
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FDX1L (ferredoxin 1-like) is a gene encoding mitochondrial protein whose primary function is to participate in the biosynthesis of iron-sulfur clusters (Fe-S clusters). FDX1L is closely related to the assembly of iron-sulfur clusters and is the second component in the biosynthesis mechanism of iron-sulfur clusters. Studies have shown that FDX1L is widely expressed in human cells, especially in the central nervous system. In addition, mutations in FDX1L can lead to mitochondrial myopathy, manifested by a significant reduction in the activity of respiratory chain complexes I, II, and III. The function of FDX1L is different from that of FDX1 (ferredoxin 1). FDX1 is mainly involved in the synthesis of steroid hormones, while FDX1L focuses on the biosynthesis of iron-sulfur clusters. This functional difference allows FDX1L to play an important role in maintaining homeostasis of iron-sulfur clusters in the cell.

{{ptg:RelatedPrimaryAntibodies}}