Anticorps Recombinant de lapin anti-FDXR

FDXR Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251211C10

N° de cat : 86431-1-PBS

Synonymes

ADR, ADXR, EC:1.18.1.6, Ferredoxin reductase, Ferredoxin--NADP(+) reductase

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Galerie de données de validation

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  WB analysis using 86431-1-RR (same clone as 86431-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86431-1-RR (FDXR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86431-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86431-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86431-1-RR against Human FDXR were performed. The affinity constant is 77.5 pM.

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Informations sur le produit

86431-1-PBS cible FDXR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FDXR Protéine recombinante Ag7145
• Nom complet: ferredoxin reductase
• Masse moléculaire calculée: 54 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC063493
• Symbole du gène: FDXR
• Identification du gène (NCBI): 2232
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ferredoxin reductase (FDXR, also known as adrenodoxin reductase) is a mitochondrial membrane-associated flavoprotein. One of its functions is to transfer electrons from NADPH to the two human ferredoxin proteins, FDX1 and FDX2. FDXR is expressed in all tissues with the highest expression in tissues such as the adrenal cortex, that specialize in steroid hormone synthesis. Functionally, FDXR is suggested to be involved in various Functionally, FDXR is suggested to be involved in various. Notably, recent studies have shown that FDXR mutations are associated with mitochondrial disorders, probably due to its role in iron-sulfur cluster protein biosynthesis (PMID: 32304229). FDXR has 7 isoforms with the molecular weight of 48-58 kDa.

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