Anticorps Recombinant de lapin anti-FGD6

FGD6 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240260A6

N° de cat : 83296-4-RR

Synonymes

Zinc finger FYVE domain-containing protein 24, ZFYVE24, FYVE, RhoGEF and PH domain-containing protein 6, 240260A6

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Galerie de données de validation

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  WB analysis using 83296-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83296-4-RR (FGD6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83296-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83296-4-RR against Human FGD6 were performed. The affinity constant is 10.7 nM.

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Applications testées

• Résultats positifs en WB: cellules K-562, cellules A549, cellules HEK-293, cellules HeLa, cellules Jurkat

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

83296-4-RR cible FGD6 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FGD6 Protéine recombinante Ag22211
• Nom complet: FYVE, RhoGEF and PH domain containing 6
• Masse moléculaire calculée: 1430 aa, 161 kDa
• Poids moléculaire observé: 161 kDa
• Numéro d’acquisition GenBank: BC013319
• Symbole du gène: FGD6
• Identification du gène (NCBI): 55785
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

FGD6, also known as ZFYVE24, is localized on the Homo sapiens chromosome 12q22 and consists of 1,400 amino acids. Previous studies have reported that variations in FGD6 increase individual susceptibility to polypoidal choroidal vasculopathy. It was also demonstrated that FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts by regulating the assembly of different actin-based protein networks and activating Cdc42 at different locations.

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