Anticorps Polyclonal de lapin anti-FGFR1

FGFR1 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30358-1-PBS

Synonymes

bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK

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Galerie de données de validation

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  IP experiment of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  IP result of anti-FGFR1 (IP:30358-1-AP, 4ug; Detection:30358-1-AP 1:300) with SH-SY5Y cells lysate 770 ug. This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using FGFR1 antibody (30358-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30358-1-PBS cible FGFR1 dans les applications de IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: fibroblast growth factor receptor 1
• Masse moléculaire calculée: 820 aa, 91 kDa
• Poids moléculaire observé: 80 kDa, 95 kDa, 105 kDa
• Numéro d’acquisition GenBank: BC018128
• Symbole du gène: FGFR1
• Identification du gène (NCBI): 2260
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described.

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