Anticorps Monoclonal anti-FGL2

FGL2 Monoclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C9C5

N° de cat : 67152-1-PBS

Synonymes

FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49

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Galerie de données de validation

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  WB analysis of THP-1 using 67152-1-Ig (same clone as 67152-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 67152-1-Ig (FGL2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 67152-1-Ig (same clone as 67152-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 67152-1-Ig (FGL2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67152-1-PBS cible FGL2 dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: FGL2 Protéine recombinante Ag28619
• Nom complet: fibrinogen-like 2
• Masse moléculaire calculée: 50 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC017813
• Symbole du gène: FGL2
• Identification du gène (NCBI): 10875
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.

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