Anticorps Recombinant de lapin anti-FKBP11

FKBP11 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241912D2

N° de cat : 84478-6-PBS

Synonymes

FK506 binding protein 11, EC:5.2.1.8, 241912D2, 19 kDa FKBP, 19 kDa FK506-binding protein

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Galerie de données de validation

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  WB analysis using 84478-6-RR (same clone as 84478-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84478-6-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84478-6-PBS in a different storage buffer formulation.

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  WB analysis using 84478-6-RR (same clone as 84478-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84478-6-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84478-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84478-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84478-6-RR against Human FKBP11 were performed. The affinity constant is 1.93 nM.

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Informations sur le produit

84478-6-PBS cible FKBP11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FKBP11 Protéine recombinante Ag11368
• Nom complet: FK506 binding protein 11, 19 kDa
• Masse moléculaire calculée: 201 aa, 22 kDa
• Poids moléculaire observé: 24 kDa
• Numéro d’acquisition GenBank: BC027973
• Symbole du gène: FKBP11
• Identification du gène (NCBI): 51303
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FKBP11 (FK506 binding protein 11, also named FKBP19) was first described as predominantly expressed in secretory tissues including the pancreas and recent studies have suggested a role in beta cell survival under conditions of ER stress (PMID: 35456020). In addition, FKBP11 appears to play a role in osteoblasts and bone formation where it has been observed to associate with interferon-inducible transmembrane protein 5 (IFITM5) (PMID: 24058703).

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