Anticorps Recombinant de lapin anti-FKBP2

FKBP2 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241166B9

N° de cat : 84077-6-PBS

Synonymes

FKBP 2, FKBP 13, FK506-binding protein 2, EC:5.2.1.8, 241166B9

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Galerie de données de validation

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  WB analysis using 84077-6-RR (same clone as 84077-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84077-6-RR (FKBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84077-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84077-6-RR against Human FKBP2 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

84077-6-PBS cible FKBP2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FKBP2 Protéine recombinante Ag2255
• Nom complet: FK506 binding protein 2, 13kDa
• Masse moléculaire calculée: 142 aa, 16 kDa
• Poids moléculaire observé: 13-16 kDa
• Numéro d’acquisition GenBank: BC003384
• Symbole du gène: FKBP2
• Identification du gène (NCBI): 2286
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant (PMID:8373365).

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