Anticorps Polyclonal de lapin anti-FKBP7

FKBP7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12092-1-PBS

Synonymes

23 kDa FK506 binding protein, 23 kDa FK506-binding protein, 23 kDa FKBP, EC:5.2.1.8, FK506 binding protein 7

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Galerie de données de validation

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  WB analysis of human lung using 12092-1-AP (same clone as 12092-1-PBS)

  human lung tissue were subjected to SDS PAGE followed by western blot with 12092-1-AP (FKBP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 12092-1-AP (same clone as 12092-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 12092-1-AP (FKBP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12092-1-PBS cible FKBP7 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FKBP7 Protéine recombinante Ag2733
• Nom complet: FK506 binding protein 7
• Masse moléculaire calculée: 259 aa, 30 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC009711
• Symbole du gène: FKBP7
• Identification du gène (NCBI): 51661
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FKBP7(FK506-binding protein 7) is also named as FKBP23 and belongs to immunophilin class of proteins family. This protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites. The calculated molecular mass is about 25 kD, but becomes 33 kD following cleavage of the signal sequence(PMID:9806833). It could bind to BiP in ER in a process regulated by the concentration of Ca2+(PMID:22269648). It has 3 isoforms produced by alternative splicing.

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