Anticorps Recombinant de lapin anti-FLT3/CD135

FLT3/CD135 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

241414F8

N° de cat : PE-FcA98106

Synonymes

FLT3, FLK2, FL cytokine receptor, Fetal liver kinase-2, EC:2.7.10.1

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Galerie de données de validation

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  FC experiment of Reh using PE-FcA98106

  1x10^6 Reh cells (left) or U-937 cells (right) were surface stained with 5 ul PE Anti-Human FLT3/CD135 Rabbit Recombinant Antibody (PE-FcA98106, Clone: 241414F8) (red), or PE Rabbit IgG Isotype Control Recombinant Antibody (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Reh cells,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-FcA98106 cible FLT3/CD135 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: fms-related tyrosine kinase 3
• Masse moléculaire calculée: 993 aa, 113 kDa
• Numéro d’acquisition GenBank: BC036028
• Symbole du gène: FLT3
• Identification du gène (NCBI): 2322
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

FLT3 (also known as CD135 or FLK2) is a tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and of dendritic cells. FLT3 was originally identified by its expression in hematopoietic stem/progenitor cells (PMID: 7507245). It is important for the normal development of hematopoietic stem/progenitor cells. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

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