Anticorps Monoclonal anti-FMNL2

FMNL2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3E8C12

N° de cat : 68551-1-PBS

Synonymes

FHOD2, FLJ37546, FMNL2, formin like 2, Formin like protein 2, KIAA1902

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Galerie de données de validation

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  WB analysis using 68551-1-Ig (same clone as 68551-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68551-1-Ig (FMNL2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68551-1-PBS in a different storage buffer formulation.

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  WB analysis of hTERT-RPE1 using 68551-1-Ig (same clone as 68551-1-PBS)

  hTERT-RPE1 cells were subjected to SDS PAGE followed by western blot with 68551-1-Ig (FMNL2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68551-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68551-1-PBS cible FMNL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: FMNL2 Protéine recombinante Ag34164
• Nom complet: formin-like 2
• Poids moléculaire observé: 140-150 kDa
• Numéro d’acquisition GenBank: BC167159
• Symbole du gène: FMNL2
• Identification du gène (NCBI): 114793
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Formin-like 2 (FMNL2), also known as FRL3 or FHOD2, a member of the diaphanous-related formins, contains a GTPase-binding domain and autoregulatory domains, and is proposed to function as a downstream effector of Rho family guanosine triphosphatases (GTPases) (PMID:15950879). FMNL2 mRNA is expressed in many normal tissues and dysregulated in several cancers such as colorectal cancer, melanoma and involved in invasive behaviours and progression of cancer cells.

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