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Anticorps Polyclonal de lapin anti-FNIP1

FNIP1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28380-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using FNIP1 Polyclonal antibody (28380-1-AP)

    WB analysis using 28380-1-AP (same clone as 28380-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28380-1-AP (FNIP1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. . This data was developed using the same antibody clone with 28380-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of C2C12 cells using FNIP1 Polyclonal antibody (28380-1-AP)

    IF Staining of C2C12 using 28380-1-AP (same clone as 28380-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed C2C12 cells using FNIP1 antibody (28380-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28380-1-PBS in a different storage buffer formulation.

Informations sur le produit

28380-1-PBS cible FNIP1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène FNIP1 Protéine recombinante Ag28976
Nom complet folliculin interacting protein 1
Masse moléculaire calculée 508 aa, 57 kDa
Poids moléculaire observé 130-150 kDa
Numéro d’acquisition GenBankBC001956
Symbole du gène FNIP1
Identification du gène (NCBI) 96459
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Folliculin-interacting protein 1 (FNIP1) forms a complex with the protein folliculin (FLCN), together acting as guanosine triphosphate (GTP)-activating protein (GAP) for RagC. The FNIP1-FLCN complex has emerged as an amino acid sensor to the mechanistic target of rapamycin complex 1 (mTORC1), involved in how amino acids control TFEB activation. AMPK phosphorylation of FNIP1 induces lysosomal and mitochondrial biogenesis (PMID: 37079666)

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