Anticorps Polyclonal de lapin anti-FNIP2

FNIP2 Polyclonal Antibody for IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31283-1-PBS

Synonymes

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Galerie de données de validation

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  IP experiment of HEK-293 using 31283-1-AP (same clone as 31283-1-PBS)

  IP result of anti-FNIP2 (IP:31283-1-AP, 4ug; Detection:31283-1-AP 1:500) with HEK-293 cells lysate 1470 ug. This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31283-1-AP (FNIP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31283-1-AP (FNIP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31283-1-PBS cible FNIP2 dans les applications de IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FNIP2 Protéine recombinante Ag35014
• Nom complet: folliculin interacting protein 2
• Poids moléculaire observé: 125 kDa
• Numéro d’acquisition GenBank: BC166693
• Symbole du gène: FNIP2
• Identification du gène (NCBI): 57600
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. FNIP2 was found to bind to the C terminus of FLCN and to AMPK, like FNIP1. FNIP2 competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PMID: 18403135).

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