Anticorps Recombinant de lapin anti-FNIP2

FNIP2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241638F2

N° de cat : 84371-2-PBS

Synonymes

241638F2, FNIP1 like protein, FNIPL, KIAA1450

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Galerie de données de validation

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  WB analysis of A549 using 84371-2-RR (same clone as 84371-2-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 84371-2-RR (FNIP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84371-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01240-1

  Cytometric bead array standard curve of MP01240-1, FNIP2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84371-2-PBS. Detection antibody: 84371-1-PBS. Standard: Ag35014. Range: 0.469-60 ng/mL.

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  Affinity and Kinetic Characterization of 84371-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84371-2-RR against Human FNIP2 were performed. The affinity constant is 4.85 nM.

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Informations sur le produit

84371-2-PBS cible FNIP2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FNIP2 Protéine recombinante Ag35014
• Nom complet: folliculin interacting protein 2
• Poids moléculaire observé: 125 kda
• Numéro d’acquisition GenBank: BC166693
• Symbole du gène: FNIP2
• Identification du gène (NCBI): 57600
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. FNIP2 was found to bind to the C terminus of FLCN and to AMPK, like FNIP1. FNIP2 competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PMID: 18403135).

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