Anticorps Recombinant de lapin anti-FOXK2
FOXK2 Recombinant Antibody for IF/ICC
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
IF/ICC
Conjugaison
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
240692A5
N° de cat : CL488-83735-4
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IF/ICC | cellules A431, |
Dilution recommandée
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
CL488-83735-4 cible FOXK2 dans les applications de IF/ICC et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Recombinant |
| Type | Anticorps |
| Immunogène | FOXK2 Protéine recombinante Ag33625 |
| Nom complet | forkhead box K2 |
| Masse moléculaire calculée | 69 kDa |
| Poids moléculaire observé | 69-79 kDa |
| Numéro d’acquisition GenBank | NM_004514.3 |
| Symbole du gène | FOXK2 |
| Identification du gène (NCBI) | 3607 |
| Conjugaison | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Conditions de stockage | Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
FOXK2 (forkhead box K2), also known as ILF and ILF1. FOXK2 is localized at nucleus and cytoplasm. It is also expected to be expressed in testis, brain and lymphoid and non-lymphoid cells (PMID: 1339390). The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. And its molecular weight is 69 kDa. Anett Marais demonstrate that FOXK2 is phosphorylated in a cell cycle-dependent manner. This phosphorylation peaks during M phase and is mediated by CDK·cyclin complexes. FOXK2 exhibits a periodic rise in its phosphorylation levels during the cell cycle, with hyperphosphorylation occurring in mitotic cells (PMID: 20810654).
Protocole
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 FOXK2 antibody CL488-83735-4 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
