Anticorps Recombinant de lapin anti-FOXN2

FOXN2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240896C8

N° de cat : 83899-2-PBS

Synonymes

240896C8, forkhead box N2, Forkhead box protein N2, HTLF, Human T-cell leukemia virus enhancer factor

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Galerie de données de validation

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  WB analysis using 83899-2-RR (same clone as 83899-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83899-2-RR (FOXN2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83899-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00842-3

  Cytometric bead array standard curve of MP00842-3, FOXN2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83899-2-PBS. Detection antibody: 83899-4-PBS. Standard: Ag5126. Range: 1.563-100 ng/mL.

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  Affinity and Kinetic Characterization of 83899-2-RR

  Biolayer interferometry (BLl) kinetic assays of 83899-2-RR against Human FOXN2 were performed. The affinity constant is 2.90 nM.

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Informations sur le produit

83899-2-PBS cible FOXN2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FOXN2 Protéine recombinante Ag5126
• Nom complet: forkhead box N2
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: BC063305
• Symbole du gène: FOXN2
• Identification du gène (NCBI): 3344
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Forkhead box N2 (FOXN2), a member of the FOX transcription factor family, has been found to play key roles in various types of human cancers. A recent report has indicated that FOXN2 is downregulated and serves as a tumor suppressor in T-cell leukemia. Moreover, downregulation of FOXN2 is closely associated with adverse prognosis in adult glioblastoma multiforme treated with radiotherapy or chemotherapy. (PMID: 30655703)

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