Anticorps Polyclonal de lapin anti-FOXN3

FOXN3 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25399-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 25399-1-AP (same clone as 25399-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25399-1-AP (FOXN3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25399-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 25399-1-AP (same clone as 25399-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using FOXN3 antibody (25399-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25399-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25399-1-PBS cible FOXN3 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FOXN3 Protéine recombinante Ag21929
• Nom complet: forkhead box N3
• Masse moléculaire calculée: 490 aa, 54 kDa
• Poids moléculaire observé: 54 kDa
• Numéro d’acquisition GenBank: BC007506
• Symbole du gène: FOXN3
• Identification du gène (NCBI): 1112
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

As transcriptional regulators, the FOX protein family regulates the development of tissues, embryos as well as carbohydrate and lipid metabolism. Forkhead box N3 (FOXN3), also known as checkpoint suppressor 1 (CHES1), is initially identified from yeast and belongs to the FOX protein family as it contains a conserved FOX DNA binding domain in its N-terminal(PMID: 36450706). FOXN3 had been dysregulated in many types of malignancies including melanoma, osteosarcoma, hepatocellular carcinoma and breast cancer, and its expression level is strongly associated with progression and prognosis of patients(PMID: 31214487).

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