- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-FOXP2
FOXP2 Polyclonal Antibody for WB, IP, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, rat, souris
Applications
WB, IHC, IF, IP, CoIP, ELISA
Conjugaison
Non conjugué
N° de cat : 20529-1-AP
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | cellules HCT 116, cellules Neuro-2a, tissu cérébral de rat, tissu cérébral de souris, tissu pulmonaire de souris |
| Résultats positifs en IP | tissu splénique de souris |
Dilution recommandée
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunoprécipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| KD/KO | See 1 publications below |
| WB | See 2 publications below |
| IHC | See 4 publications below |
| IF | See 2 publications below |
| CoIP | See 1 publications below |
Informations sur le produit
20529-1-AP cible FOXP2 dans les applications de WB, IHC, IF, IP, CoIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris
| Réactivité | Humain, rat, souris |
| Réactivité citée | rat, Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | FOXP2 Protéine recombinante Ag14391 |
| Nom complet | forkhead box P2 |
| Masse moléculaire calculée | 80 kDa |
| Poids moléculaire observé | 70-80 kDa |
| Numéro d’acquisition GenBank | BC018016 |
| Symbole du gène | FOXP2 |
| Identification du gène (NCBI) | 93986 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
FOXP2, Forkhead box protein P2, is associated with speech and language development (PMID: 24765219). FOXP2 is expressed in the brain, lungs, heart and gut. In the brain, it is widely expressed in sensory, limbic and motor structures(PMID: 10880297, PMID:15685218). Mutations in FOXP2 caused the severe speech and language disorder developmental verbal dyspraxia (PMID: 15877281). FOXP2 was detected 2 isoforms of 70 kDa and 80-82 kDa (PMID: 15056696, PMID: 29360038, PMID: 17999357).
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for FOXP2 antibody 20529-1-AP | Download protocol |
| IP protocol for FOXP2 antibody 20529-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Elife FoxP2 isoforms delineate spatiotemporal transcriptional networks for vocal learning in the zebra finch. | ||
Mol Ther Nucleic Acids circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways. | ||
J Cancer Low expression of FOXP2 predicts poor survival and targets caspase-1 to inhibit cell pyroptosis in colorectal cancer.
| ||
BMC Biol GnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion | ||
Commun Biol FOXP2 overexpression upregulates LAMA4 expression and thereby alleviates preeclampsia by regulating trophoblast behavior | ||
Cell Rep The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Reyes (Verified Customer) (10-18-2024) | FOXP2 (in green) worked marking my neurons (in red) in FFPE human brain tissue, although other tests to check the specificity of the layer need to be performed.
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