Anticorps Polyclonal de lapin anti-FOXQ1

• Phare
• Validé par KD/KO

FOXQ1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

6

N° de cat : 23718-1-AP

Synonymes

Forkhead box protein Q1, forkhead box Q1, FOXQ1, HFH 1, HFH1, HNF 3/forkhead like protein 1

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Galerie de données de validation

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  WB analysis of mouse kidney using 23718-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 23718-1-AP (FOXQ1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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  WB analysis of rat kidney using 23718-1-AP

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 23718-1-AP (FOXQ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu rénal de souris, tissu rénal de rat

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 2 publications below
• WB: See 6 publications below
• IHC: See 1 publications below
• IF: See 1 publications below
• IP: See 1 publications below

Informations sur le produit

23718-1-AP cible FOXQ1 dans les applications de WB, IP, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FOXQ1 Protéine recombinante Ag20545
• Nom complet: forkhead box Q1
• Masse moléculaire calculée: 403 aa, 41 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC053850
• Symbole du gène: FOXQ1
• Identification du gène (NCBI): 94234
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Forkhead box Q1 (FOXQ1, also known as HFH1), a member of the FOX gene family, contains the core DNA binding domain, whereas the flanking wings of FOXQ1 contribute to its sequence specificity. FOXQ1 is known to repress the promoter activity of smooth muscle-specific genes, such as telokin and SM22α. FOXQ1 expression is regulated by Hoxa1 in embryonic stem cells. [PMID:15722554, 8139574] As a transcription factor, FOXQ1 represses the promoter activity of smooth muscle-specific genes, such as telokin and SM22α, in A10 vascular muscle cells [PMID:10896677].

Publications

Species	Application	Title
human	WB	Breast Cancer Res; Long noncoding RNA PVT1 promotes breast cancer proliferation and metastasis by binding miR-128-3p and UPF1.; Authors - Shuiyi Liu
human	WB	Front Oncol; The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.; Authors - Zhichao Jin ; KD Validated
human	WB	Mol Carcinog; Monocarboxylate transporter 1 is a novel target for breast cancer stem like-cell inhibition by diallyl trisulfide.; Authors - Su-Hyeong Kim
human	WB	Cancer Prev Res (Phila); The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer.; Authors - Su-Hyeong Kim
human	WB	J Cell Physiol; Decreased CRISPLD2 expression impairs osteogenic differentiation of human mesenchymal stem cells during in vitro expansion; Authors - Weiqiong Rong
mouse,human	WB,IHC,IF,IP	Cell Death Dis; FOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis; Authors - Changhao Wu ; KD Validated