Anticorps Polyclonal de lapin anti-FPR2

FPR2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30989-1-PBS

Synonymes

ALXR, FMLP R I, FMLP R II, FMLP related receptor I, FMLP-related receptor I

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Galerie de données de validation

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  WB analysis of HEK-293 using 30989-1-AP (same clone as 30989-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 30989-1-AP (FPR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30989-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30989-1-AP (same clone as 30989-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30989-1-AP (FPR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30989-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30989-1-PBS cible FPR2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FPR2 Protéine recombinante Ag34304
• Nom complet: formyl peptide receptor 2
• Masse moléculaire calculée: 351 aa, 39 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC029125
• Symbole du gène: FPR2
• Identification du gène (NCBI): 2358
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The formyl peptide receptors (FPRs) are a group of G protein-coupled chemoattractant receptors that play important roles in host defense and inflammation (PMID: 28335409). In humans, three different isoforms are expressed (FPR1, FPR2, and FPR3). FPR2, also known as FPRL1 or ALX, is expressed by many cell types including monocytes, neutrophils, macrophages, astrocytoma cells, and epithelial cells. FPR2 conveys the biological functions of a variety of ligands, including N-formyl-methionyl peptides, the pro-resolution mediators annexin A1 (AnxA1) and lipoxin A4, as well as the activating and proinflammatory protein serum amyloid A (PMID: 22610094).

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