Anticorps Monoclonal anti-FSH beta

FSH beta Monoclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B10A11

N° de cat : 67131-1-PBS

Synonymes

FSHB, 1B10A11, Follicle-stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta

---

Galerie de données de validation

• 

  IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 67131-1-Ig (FSH beta antibody) at dilution of 1:1000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 67131-1-Ig (FSHB antibody) at dilution of 1:1000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pituitary adenoma using 67131-1-Ig (same clone as 67131-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pituitary adenoma tissue slide using 67131-1-Ig (FSH beta antibody) at dilution of 1:1000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 67131-1-Ig (same clone as 67131-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using FSH beta antibody (67131-1-Ig, Clone: 1B10A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

67131-1-PBS cible FSH beta dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: FSH beta Protéine recombinante Ag13788
• Nom complet: follicle stimulating hormone, beta polypeptide
• Masse moléculaire calculée: 129 aa, 15 kDa
• Numéro d’acquisition GenBank: BC113488
• Symbole du gène: FSHB
• Identification du gène (NCBI): 2488
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The FSHB gene encodes the beta subunit of follicle-stimulating hormone (FSH), particularly expressed in gonadotroph cells within the anterior pituitary gland and plays a critical role in the regulation of gonadal function, pubertal maturation and reproductive processes in mammals. The transcription of the FSHB gene is critical for the production of the FSH hormone(PMID:28281143). And FSH is required for ovarian folliculogenesis in females, in males it promotes spermatogenesis in conjunction with testosterone(PMID:11739331). Mutations in FSHB gene would result in infertility both in men and women (PMID: 23766128).

{{ptg:RelatedPrimaryAntibodies}}