Anticorps Recombinant de lapin anti-FTL

FTL Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251048G12

N° de cat : 81166-3-PBS

Synonymes

Ferritin, Ferritin light chain, Ferritin L subunit

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Galerie de données de validation

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  WB analysis using 81166-3-RR (same clone as 81166-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81166-3-RR (FTL antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81166-3-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 81166-3-RR (same clone as 81166-3-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed A549 cells using FTL antibody (81166-3-RR, Clone: 251048G12 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 81166-3-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 81166-3-RR (same clone as 81166-3-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using FTL antibody (81166-3-RR, Clone: 251048G12 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 81166-3-PBS in a different storage buffer formulation.

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Informations sur le produit

81166-3-PBS cible FTL dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FTL Protéine recombinante Ag20637
• Nom complet: ferritin, light polypeptide
• Masse moléculaire calculée: 19 kDa
• Poids moléculaire observé: 18 kDa
• Numéro d’acquisition GenBank: BC008439
• Symbole du gène: Ferritin light chain
• Identification du gène (NCBI): 2512
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FTL belongs to the ferritin family. It stores iron in a soluble, non-toxic, readily available form. FTL is important for iron homeostasis. It plays a role in delivery of iron to cells. FTL mediates iron uptake in capsule cells of the developing kidney. Mutation of FTL will cause hereditary hyperferritinemia-cataract syndrome (HHCS) or neurodegeneration with brain iron accumulation type 3 (NBIA3). Ferritin light polypeptide (FTL) and ferritin heavy polypeptide (FTH1) were the main constituents the striatum and cerebellar cortex revealed.

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