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Anticorps Polyclonal de lapin anti-FUT2

FUT2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20288-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using FUT2 Polyclonal antibody (20288-1-AP)

    WB analysis using 20288-1-AP (same clone as 20288-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20288-1-AP (FUT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20288-1-PBS in a different storage buffer formulation.

Informations sur le produit

20288-1-PBS cible FUT2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène FUT2 Protéine recombinante Ag14047
Nom complet fucosyltransferase 2 (secretor status included)
Masse moléculaire calculée 343 aa, 39 kDa
Poids moléculaire observé35-39 kDa
Numéro d’acquisition GenBankBC001899
Symbole du gène FUT2
Identification du gène (NCBI) 2524
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fucosyltransferase 2 (FUT2) is a key enzyme that catalyzes the transfer of fucose to the terminal galactose of type 1 or type 2 disaccharide via α1,2-linkage. FUT2 gene codes for the alpha(1,2)fucosyltransferase responsible for the synthesis of the H antigen, which is the precursor of the ABO histo-blood group antigens in body fluids and on the intestinal mucosa (PMID: 19487333). FUT2 is highly expressed in lung adenocarcinoma (LUAD) and plays a vital role in the tumorigenesis of LUAD (PMID: 36552800). FUT2 has a calculated molecular mass of ~39 kDa, and the 70kDa band might be the glycosylated form.

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