Anticorps Polyclonal de lapin anti-FXI

FXI Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24321-1-PBS

Synonymes

F11, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, EC:3.4.21.27, PTA

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Galerie de données de validation

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  WB analysis using 24321-1-AP (same clone as 24321-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24321-1-AP (FXI antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24321-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24321-1-PBS cible FXI dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FXI Protéine recombinante Ag18004
• Nom complet: coagulation factor XI
• Masse moléculaire calculée: 625 aa, 70 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC119014
• Symbole du gène: F11
• Identification du gène (NCBI): 2160
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Factor XI (FXI) is the zymogen of a blood coagulation protease, factor XIa (FXIa), that contributes to hemostasis by activating factor IX. Factor XI is a precursor of an S1 serine protease found in blood plasma. When activated to FXIa, it plays a crucial role in forming and stabilizing fibrin by triggering the activation of factor IX (PMID: 38545505). FXI has 2 isoforms with the molecular mass of 70 kDa and 64 kDa. Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.

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