Anticorps Polyclonal de lapin anti-FXR1

• Phare
• Validé par KD/KO

FXR1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13194-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13194-1-AP (same clone as 13194-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13194-1-AP (FXR1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse heart using 13194-1-AP (same clone as 13194-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 13194-1-AP (FXR1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse skeletal muscle using 13194-1-AP (same clone as 13194-1-PBS)

  IP result of anti-FXR1 (IP:13194-1-AP, 3ug; Detection:13194-1-AP 1:800) with mouse skeletal muscle tissue lysate 8000ug. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 13194-1-AP (FXR1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 13194-1-AP (FXR1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 13194-1-AP (same clone as 13194-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using FXR1 antibody (13194-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 13194-1-AP (same clone as 13194-1-PBS)

  Immunofluorescent analysis of HepG2 cells using 13194-1-AP (FXR1 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13194-1-PBS cible FXR1 dans les applications de WB, IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FXR1 Protéine recombinante Ag3873
• Nom complet: fragile X mental retardation, autosomal homolog 1
• Masse moléculaire calculée: 621 aa, 70 kDa
• Poids moléculaire observé: 70-80 kDa
• Numéro d’acquisition GenBank: BC028983
• Symbole du gène: FXR1
• Identification du gène (NCBI): 8087
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of inflammation in host defence against infection and in autoimmune disease. Its production is controlled post-transcriptionally by multiple RNA-binding proteins that interact with the TNF-alpha AU-rich element and regulate its expression; Fragile X mental retardation-related protein 1 (FXR1) is one of these. FXR1 (fragile-X-mental retardation-related protein 1) are RNA-binding proteins that have been demonstrated to impact miRNA-mediated, post-transcriptional gene regulation, and required for embryonic and postnatal development of muscle tissue. It can regulate intracellular transport and local translation of certain mRNAs. The FXR1 exists some isoforms with the MW 69 kDa and 60 kDa.

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