Anticorps Recombinant de lapin anti-Fas/CD95

Fas/CD95 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

240340E11

N° de cat : CL488-98034

Synonymes

FAS, APT1, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, APO-1

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Galerie de données de validation

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  FC experiment of human PBMCs using CL488-98034

  1x10^6 human PBMCs were surface stained with APC Anti-Human CD45RO, and 5 ul CoraLite® Plus 488 Anti-Human Fas/CD95 Rabbit Recombinant Antibody (CL488-98034, Clone:240340E11) (right), or Isotype Control (left). Cells were not fixed.

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  FC experiment of human PBMCs using CL488-98034

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 488 Anti-Human Fas/CD95 Rabbit Recombinant Antibody (CL488-98034, Clone:240340E11) (red), or Isotype Control (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-98034 cible Fas/CD95 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: Fas (TNF receptor superfamily, member 6)
• Masse moléculaire calculée: 38 kDa
• Numéro d’acquisition GenBank: NM_000043.6
• Symbole du gène: Fas/CD95
• Identification du gène (NCBI): 355
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

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