Anticorps Recombinant de lapin anti-Fas/CD95

Fas/CD95 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241229C11

N° de cat : CL647-98135

Synonymes

CD95, Fas, 241229C11, APO 1, APT1

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Galerie de données de validation

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  FC experiment of mouse thymocytes using CL647-98135

  1x10^6 mouse thymocytes were surface stained with CoraLite® Plus 405 Anti-Mouse CD8a, and 0.25 ug CoraLite® Plus 647 Anti-Mouse Fas/CD95 Rabbit RecAb (CL647-98135, Clone: 241229C11) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse thymocytes using CL647-98135

  1x10^6 mouse thymocytes were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse Fas/CD95 Rabbit RecAb (CL647-98135, Clone: 241229C11) (red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: thymocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98135 cible Fas/CD95 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Fas/CD95 Protéine recombinante Eg1376
• Nom complet: Fas (TNF receptor superfamily member 6)
• Masse moléculaire calculée: 37kDa
• Numéro d’acquisition GenBank: NM_007987.2
• Symbole du gène: Fas/CD95
• Identification du gène (NCBI): 14102
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.

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