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Anticorps Recombinant de lapin anti-FceR1a

FceR1a Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241848D1

N° de cat : 84662-3-PBS

Synonymes

FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using FceR1a Recombinant antibody (84662-3-RR)

    WB analysis using 84662-3-RR (same clone as 84662-3-PBS)

    Human testis was subjected to SDS PAGE followed by western blot with 84662-3-RR (Fc epsilon RI alpha antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84662-3-PBS in a different storage buffer formulation.

Informations sur le produit

84662-3-PBS cible FceR1a dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Masse moléculaire calculée30kDa
Poids moléculaire observé55-65 kDa
Numéro d’acquisition GenBankNM_001387280.1
Symbole du gène FceR1a
Identification du gène (NCBI) 2205
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316). The calculated molecular weight of FceR1a is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).

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