Anticorps Recombinant de lapin anti-FceR1a

FceR1a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242008G6

N° de cat : 98289-1-PBS

Synonymes

242008G6, Fce1a, FceR1, FcERI, Fcr 5

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Galerie de données de validation

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  FC experiment of MC/9 using 98289-1-RR (same clone as 98289-1-PBS)

  1x10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse Fc-epsilon RI-alpha (FcERI) Rabbit RecAb (98289-1-RR, Clone: 242008G6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98289-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98289-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98289-1-RR against Mouse FceR1a were performed. The affinity constant is below 1 pM.

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Informations sur le produit

98289-1-PBS cible FceR1a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FceR1a Protéine recombinante Eg1740
• Nom complet: Fc receptor, IgE, high affinity I, alpha polypeptide
• Masse moléculaire calculée: 29 kDa
• Numéro d’acquisition GenBank: NM_010184.2
• Symbole du gène: FceR1a
• Identification du gène (NCBI): 14125
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).

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