Anticorps Recombinant de lapin anti-FceR1a

FceR1a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242008G6

N° de cat : 98289-1-RR

Synonymes

242008G6, Fce1a, FceR1, FcERI, Fcr 5

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Galerie de données de validation

• 

  FC experiment of MC/9 using 98289-1-RR

  1x10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse Fc-epsilon RI-alpha (FcERI) Rabbit RecAb (98289-1-RR, Clone: 242008G6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98289-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98289-1-RR against Mouse FceR1a were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: cellules MC/9,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98289-1-RR cible FceR1a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FceR1a Protéine recombinante Eg1740
• Nom complet: Fc receptor, IgE, high affinity I, alpha polypeptide
• Masse moléculaire calculée: 29 kDa
• Numéro d’acquisition GenBank: NM_010184.2
• Symbole du gène: FceR1a
• Identification du gène (NCBI): 14125
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).

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