Anticorps Recombinant de lapin anti-Fibrillin 1

Fibrillin 1 Recombinant Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240960G12

N° de cat : 83836-4-PBS

Synonymes

FBN1, 240960G12, Asprosin, FBN, Fibrillin-1

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Galerie de données de validation

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  WB analysis of HeLa using 83836-4-RR (same clone as 83836-4-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 83836-4-RR (Fibrillin 1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83836-4-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 83836-4-RR (same clone as 83836-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 83836-4-RR (Fibrillin 1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer(pH9). This data was developed using the same antibody clone with 83836-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83836-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83836-4-RR against Human Fibrillin 1 were performed. The affinity constant is 51.3 nM.

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Informations sur le produit

83836-4-PBS cible Fibrillin 1 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Fibrillin 1 Protéine recombinante Ag30283
• Nom complet: fibrillin 1
• Poids moléculaire observé: 350 kDa
• Numéro d’acquisition GenBank: BC146854
• Symbole du gène: Fibrillin 1
• Identification du gène (NCBI): 2200
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibrillin-1 belongs to the fibrillin family. Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Defects in Fibrillin-1 are a cause of Marfan syndrome (MFS), isolated ectopia lentis (EL), Weill-Marchesani syndrome autosomal dominant (ADWMS), Shprintzen-Goldberg craniosynostosis syndrome (SGS) or MASS syndrome.

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