Anticorps Polyclonal de lapin anti-Fibrinogen Alpha Chain

• Phare
• Validé par KD/KO

Fibrinogen Alpha Chain Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20645-1-PBS

Synonymes

FGA, Fib2, Fibrinopeptide A

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Galerie de données de validation

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  WB analysis of mouse liver using 20645-1-AP (same clone as 20645-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 20645-1-AP (Fibrinogen alpha chain antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20645-1-PBS cible Fibrinogen Alpha Chain dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Fibrinogen Alpha Chain Protéine recombinante Ag9567
• Nom complet: fibrinogen alpha chain
• Masse moléculaire calculée: 866 aa, 95 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC020764
• Symbole du gène: Fibrinogen Alpha Chain
• Identification du gène (NCBI): 2243
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGA is the alpha chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide A is cleaved from FGA by thrombin.

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