Anticorps Monoclonal anti-Fibrinogen Gamma Chain

Fibrinogen Gamma Chain Monoclonal Antibody for WB, IHC, IF/ICC, ELISA

Hôte / Isotype

Mouse / IgM

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

2B2B8

N° de cat : 66158-1-PBS

Synonymes

FGG, 2B2B8, PRO2061

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Galerie de données de validation

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  WB analysis of L02 using 66158-1-Ig (same clone as 66158-1-PBS)

  L02 cells were subjected to SDS PAGE followed by western blot with 66158-1-Ig (Fibrinogen gamma chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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  WB analysis of human peripheral blood leukocyte using 66158-1-Ig (same clone as 66158-1-PBS)

  human peripheral blood leukocyte were subjected to SDS PAGE followed by western blot with 66158-1-Ig (Fibrinogen Gamma Chain antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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  WB analysis of human peripheral blood platelets using 66158-1-Ig (same clone as 66158-1-PBS)

  human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 66158-1-Ig (Fibrinogen Gamma Chain antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66158-1-Ig (same clone as 66158-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66158-1-Ig (Fibrinogen Gamma Chain antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66158-1-Ig (same clone as 66158-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66158-1-Ig (Fibrinogen Gamma Chain antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66158-1-Ig (same clone as 66158-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66158-1-Ig (Fibrinogen gamma chain antibody at dilution of 1:50. This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66158-1-Ig (same clone as 66158-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66158-1-Ig (Fibrinogen gamma chain antibody at dilution of 1:50. This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

• 

  IF Staining of L02 using 66158-1-Ig (same clone as 66158-1-PBS)

  Immunofluorescent analysis of L02 cells using 66158-1-Ig (Fibrinogen gamma chain antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). This data was developed using the same antibody clone with 66158-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66158-1-PBS cible Fibrinogen Gamma Chain dans les applications de WB, IHC, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgM
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Fibrinogen Gamma Chain Protéine recombinante Ag8817
• Nom complet: fibrinogen gamma chain
• Masse moléculaire calculée: 453aa,52 kDa; 437aa,50 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC007044
• Symbole du gène: Fibrinogen Gamma Chain
• Identification du gène (NCBI): 2266
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Chromatographie d'affinité thiophilique
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.

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