Anticorps Monoclonal anti-Fibromodulin

• Phare
• Validé par KD/KO

Fibromodulin Monoclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3E9D10

N° de cat : 60108-1-PBS

Synonymes

fibromodulin, FM, FMOD, KSPG fibromodulin, SLRR2E

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Galerie de données de validation

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  WB analysis of human kidney using 60108-1-Ig (same clone as 60108-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 60108-1-Ig (Fibromodulin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human kidney using 60108-1-Ig (same clone as 60108-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 60108-1-Ig (Fibromodulin antibody) at dilution of 1:250 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human stomach using 60108-1-Ig (same clone as 60108-1-PBS)

  human stomach tissue were subjected to SDS PAGE followed by western blot with 60108-1-Ig (Fibromodulin antibody) at dilution of 1:250 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 60108-1-Ig (Fibromodulin antibody) at dilution of 1:300 (under 10x lens). This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 60108-1-Ig (Fibromodulin antibody) at dilution of 1:300 (under 40x lens). This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60108-1-PBS cible Fibromodulin dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Fibromodulin Protéine recombinante Ag4030
• Nom complet: fibromodulin
• Masse moléculaire calculée: 376 aa, 43 kDa
• Numéro d’acquisition GenBank: BC035281
• Symbole du gène: Fibromodulin
• Identification du gène (NCBI): 2331
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibromodulin (FMOD), an extracellular matrix protein, belongs to the small leucine-rich proteoglycan family. Fibromodulin is a collagen-binding protein present in many types of connective tissues, e.g. cartilage, tendon, skin, sclera and cornea (PMID: 2531085). It is involved in fibrillogenesis, cell adhesion, and cytokine activity modulation (PMID: 15741214). Fibromodulin may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. The calculated molecular mass of fibromodulin is 43 kDa, extracellular fibromodulin appears as one single band of 59 kDa due to glycosylation (PMID: 2531085; 22138190).

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