Anticorps Polyclonal de lapin anti-Follistatin

Follistatin Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27350-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 27350-1-AP (same clone as 27350-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27350-1-AP (Follistatin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

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  WB analysis using 27350-1-AP (same clone as 27350-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27350-1-AP (Follistatin antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 27350-1-AP (same clone as 27350-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using Follistatin antibody (27350-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27350-1-PBS cible Follistatin dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Follistatin Protéine recombinante Ag26401
• Nom complet: follistatin
• Masse moléculaire calculée: 33 aa, 7 kDa
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC004107
• Symbole du gène: Follistatin
• Identification du gène (NCBI): 10468
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Follistatin (FST) is a member of the tissue growth factor β family and is a secreted glycoprotein that antagonizes many members of the family, including activin A, growth differentiation factor11 , and myostatin. It binds activin A with high affinity and whose expression can be induced by activin A and several other pro-inflammatory cytokines. Activin A-follistatin complexes are biologically inactive and bind to cell surface heparan sulphate-containing proteoglycans for internalisation and degradation. It has also been found to play a significant role in the management of skeletal muscle size and mass. It also has important roles in early embryonic development, differentiation of ovarian granulosa cells, liver fibrosis and polycystic ovarian syndrome.

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