Anticorps Polyclonal de lapin anti-Frizzled 2

• Phare
• Validé par KD/KO

Frizzled 2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24272-1-PBS

Synonymes

FZD2, Frizzled-2, Fz 2, Fz-2, FzE2

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Galerie de données de validation

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  WB analysis using 24272-1-AP (same clone as 24272-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 24272-1-AP (same clone as 24272-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat kidney using 24272-1-AP (same clone as 24272-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 24272-1-AP (Frizzled 2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 24272-1-AP (Frizzled 2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24272-1-PBS cible Frizzled 2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Frizzled 2 Protéine recombinante Ag18003
• Nom complet: frizzled homolog 2 (Drosophila)
• Masse moléculaire calculée: 565 aa, 64 kDa
• Poids moléculaire observé: 64-70 kDa
• Numéro d’acquisition GenBank: BC113402
• Symbole du gène: Frizzled 2
• Identification du gène (NCBI): 2535
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Frizzled 2(FZD2) also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. FZD2 is an important receptor in the Wnt pathway, which is highly expressed in malignant tumors and helps regulate multiple tumor behaviors. Its expression level is related to prognosis. Moreover, high level of FZD2 had significant correlation with poor prognosis in Breast cancer (BC) patients(PMID: 33832493).

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