Anticorps Polyclonal de lapin anti-G6PC2

G6PC2 Polyclonal Antibody for IHC, IF-P, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF-P, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18074-1-PBS

Synonymes

G6Pase 2, IGRP

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Galerie de données de validation

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  IP experiment of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

  IP result of anti-G6PC2 (IP:18074-1-AP, 4ug; Detection:18074-1-AP 1:500) with mouse pancreas tissue lysate 2480 ug. This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 18074-1-AP (G6PC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 18074-1-AP (G6PC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse pancreas tissue using G6PC2 antibody (18074-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18074-1-PBS cible G6PC2 dans les applications de IHC, IF-P, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: G6PC2 Protéine recombinante Ag12764
• Nom complet: glucose-6-phosphatase, catalytic, 2
• Masse moléculaire calculée: 355 aa, 41 kDa
• Poids moléculaire observé: 38-40 kDa
• Numéro d’acquisition GenBank: BC104778
• Symbole du gène: G6PC2
• Identification du gène (NCBI): 57818
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

G6PC2, also known as IGRP, is a member of the glucose-6-phosphatase catalytic subunit (G6PC) gene family. G6PC2 catalyzes the hydrolysis of glucose-6-phosphate to glucose and inorganic phosphate within the lumen of the endoplasmic reticulum. G6PC2 is mainly expressed in pancreatic islet β-cells. G6PC2 acts to oppose the action of the beta cell glucose sensor, glucokinase, by creating a futile substrate cycle. (PMID: 37855366, PMID: 32569842, PMID: 37552875)

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