Anticorps Polyclonal de lapin anti-GABRA4

GABRA4 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12979-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse skeletal muscle using 12979-1-AP (same clone as 12979-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

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  WB analysis using 12979-1-AP (same clone as 12979-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

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  WB analysis of human kidney using 12979-1-AP (same clone as 12979-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse skeletal muscle using 12979-1-AP (same clone as 12979-1-PBS)

  IP result of anti-GABRA4 (IP:12979-1-AP, 4ug; Detection:12979-1-AP 1:500) with mouse skeletal muscle tissue lysate 2200ug. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12979-1-PBS cible GABRA4 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GABRA4 Protéine recombinante Ag3600
• Nom complet: gamma-aminobutyric acid (GABA) A receptor, alpha 4
• Masse moléculaire calculée: 554 aa, 62 kDa
• Poids moléculaire observé: 62-70 kDa
• Numéro d’acquisition GenBank: BC035055
• Symbole du gène: GABRA4
• Identification du gène (NCBI): 2557
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABRA4, encoding the extrasynaptically located α4‐subunit of the GABAA receptor, is involved in the etiology of autism. (PMID: 32028044, 32033586)

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