Anticorps Monoclonal anti-GABRG2

GABRG2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, Lapin, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H10E1

N° de cat : 68595-1-PBS

Synonymes

GABAAR subunit gamma-2, GABA(A) receptor subunit gamma-2, GABA A receptor gamma 2, ECA2, CAE2

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Galerie de données de validation

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  WB analysis using 68595-1-Ig (same clone as 68595-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68595-1-Ig (GABRG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68595-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68595-1-PBS cible GABRG2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, rat, souris

• Réactivité: Humain, Lapin, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GABRG2 Protéine recombinante Ag5489
• Nom complet: gamma-aminobutyric acid (GABA) A receptor, gamma 2
• Masse moléculaire calculée: 467 aa, 54 kDa
• Poids moléculaire observé: 40-54 kDa
• Numéro d’acquisition GenBank: BC059389
• Symbole du gène: GABRG2
• Identification du gène (NCBI): 2566
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.

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