Anticorps Polyclonal de lapin anti-GABRR1

GABRR1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF, IP, CoIP, ELISA

Conjugaison

Non conjugué

Publications(3)

N° de cat : 25899-1-AP

Synonymes

GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1

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Galerie de données de validation

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  WB analysis of mouse brain using 25899-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 25899-1-AP (GABRR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse skeletal muscle using 25899-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 25899-1-AP (GABRR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu cérébral de souris, tissu de muscle squelettique de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IF: See 1 publications below
• IP: See 1 publications below
• CoIP: See 1 publications below

Informations sur le produit

25899-1-AP cible GABRR1 dans les applications de WB, IF, IP, CoIP, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GABRR1 Protéine recombinante Ag23165
• Nom complet: gamma-aminobutyric acid (GABA) receptor, rho 1
• Masse moléculaire calculée: 479 aa, 56 kDa
• Poids moléculaire observé: 50-56 kDa
• Numéro d’acquisition GenBank: BC130344
• Symbole du gène: GABRR1
• Identification du gène (NCBI): 2569
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.

Publications

Species	Application	Title
	IF	Insect Sci; Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition; Authors - Ruijuan Wang
mouse	WB,IP,CoIP	Biochem Biophys Res Commun; Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association; Authors - Takahiro Fujimoto
mouse	WB	Transl Psychiatry; Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice; Authors - Kyosuke Yamanishi

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