Anticorps Recombinant de lapin anti-GBE1

GBE1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242705G3

N° de cat : 85143-5-PBS

Synonymes

1,4-alpha-glucan-branching enzyme, 242705G3, APBD, EC:2.4.1.18, GBE

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Galerie de données de validation

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  WB analysis using 85143-5-RR (same clone as 85143-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85143-5-RR (GBE1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85143-5-PBS in a different storage buffer formulation.

• 

  WB analysis using 85143-5-RR (same clone as 85143-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85143-5-RR (GBE1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85143-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85143-5-RR

  Biolayer interferometry (BLl) kinetic assays of 85143-5-RR against Human GBE1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

85143-5-PBS cible GBE1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GBE1 Protéine recombinante Ag14154
• Nom complet: glucan (1,4-alpha-), branching enzyme 1
• Masse moléculaire calculée: 702 aa, 80 kDa
• Poids moléculaire observé: 72 kDa
• Numéro d’acquisition GenBank: BC012098
• Symbole du gène: GBE1
• Identification du gène (NCBI): 2632
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GBE1 (glucan (1,4-alpha-), branching enzyme 1) is essential for the globular and branched structure of glycogen, increasing solubility by creating a hydrophilic surface and reducing intracellular osmotic pressure. It may serve as a potential therapeutic target for treating LUAD(PMID: 31221150). The full sequence can be further processed into a mature form of 75 kDa.

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