Anticorps Polyclonal de lapin anti-GCNT1

GCNT1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17845-1-PBS

Synonymes

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GlcNAcT, C2GNT1, C2GNT-L, Core 2 beta-1,6-N-acetylglucosaminyltransferase

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Galerie de données de validation

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  WB analysis using 17845-1-AP (same clone as 17845-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17845-1-AP (GCNT1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17845-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17845-1-AP (same clone as 17845-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17845-1-AP (GCNT1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17845-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17845-1-PBS cible GCNT1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GCNT1 Protéine recombinante Ag12264
• Nom complet: glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
• Masse moléculaire calculée: 428 aa, 50 kDa
• Poids moléculaire observé: 40-50 kDa
• Numéro d’acquisition GenBank: BC074885
• Symbole du gène: GCNT1
• Identification du gène (NCBI): 2650
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glucosaminyl (N-acetyl) transferase 1 (GCNT1, also known as C2GNT1), is a glycosyltransferase enzyme that plays an essential role in the formation of core 2 branched O-glycans that is crucial to the final definition of O-glycan structure (PMID: 37813880). GCNT1 promotes the growth of prostate tumors and regulates oncogenic gene expression pathways that are important for disease progression (PMID: 24854630).

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