Anticorps Monoclonal anti-GDAP1L1

GDAP1L1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C7A3

N° de cat : 68340-1-PBS

Synonymes

dJ881L22.1, dJ995J12.1.1, DKFZp761K228, GDAP1 L1, GDAP1L1

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Galerie de données de validation

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  WB analysis using 68340-1-Ig (same clone as 68340-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68340-1-Ig (GDAP1L1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68340-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68340-1-PBS cible GDAP1L1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GDAP1L1 Protéine recombinante Ag27717
• Nom complet: ganglioside-induced differentiation-associated protein 1-like 1
• Masse moléculaire calculée: 367 aa, 42 kDa
• Poids moléculaire observé: 38-40 kDa
• Numéro d’acquisition GenBank: BC009014
• Symbole du gène: GDAP1L1
• Identification du gène (NCBI): 78997
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751).

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